• The bone-degrading enzyme machinery: From multi-component understanding to the treatment of residues from the meat industry 

      Fernandez-Lopez, Laura; Sanches-Carrillo, Sergio; Garcia-Moyano, Antonio; Borchert, Erik; Almendral, David; Alonso, Sandra; Cea-Rama, Isabel; Miguez, Noa; Larsen, Øivind; Werner, Johannes; Makarova, Kira S; Plou, Fransisco J; Dahlgren, Thomas Gunnar; Sanz-Aparicio, Julia; Hentschel, Ute; Bjerga, Gro Elin Kjæreng; Ferrer, Manuel (Peer reviewed; Journal article, 2021)
      Many microorganisms feed on the tissue and recalcitrant bone materials from dead animals, however little is known about the collaborative effort and characteristics of their enzymes. In this study, microbial metagenomes ...
    • Characterization of a novel cold-adapted intracellular serine protease from the extremophile Planococcus halocryophilus Or1 

      Rasmussen, Casper Bøjer; Scavenius, Carsten; Thøgersen, Ida B.; Harwood, Seandean Lykke; Larsen, Øivind; Bjerga, Gro Elin Kjæreng; Stougaard, Peter; Enghild, Jan J.; Thøgersen, Mariane Schmidt (Peer reviewed; Journal article, 2023)
      The enzymes of microorganisms that live in cold environments must be able to function at ambient temperatures. Cold-adapted enzymes generally have less ordered structures that convey a higher catalytic rate, but at the ...
    • Deciphering a Marine Bone-Degrading Microbiome Reveals a Complex Community Effort 

      Borchert, Erik; Garcia-Moyano, Antonio; Sánchez-Carrillo, Sergio; Dahlgren, Thomas Gunnar; Slaby, B; Bjerga, Gro Elin Kjæreng; Ferrer, Manuel; Franzenburg, Sören; Hentschel, Ute (Peer reviewed; Journal article, 2021)
      The marine bone biome is a complex assemblage of macro- and microorganisms; however, the enzymatic repertoire to access bone-derived nutrients remains unknown. The bone matrix is a composite material made up mainly of ...
    • A ShK-like Domain from Steinernema carpocapsae with Bioinsecticidal Potential 

      Frias, Jorge; Toubarro, Duarte; Bjerga, Gro Elin Kjæreng; Puntervoll, Pål; Vicente, João B.; Reis, Rui L.; Simões, Nelson (Peer reviewed; Journal article, 2022)
      Entomopathogenic nematodes are used as biological control agents against a broad range of insect pests. We ascribed the pathogenicity of these organisms to the excretory/secretory products (ESP) released by the infective ...
    • Two-step functional screen on multiple proteinaceous substrates reveals temperature-robust proteases with a broad-substrate range 

      Garcia-Moyano, Antonio; Diaz, Yuleima; Navarro, Jose; Almendral, David; Puntervoll, Pål; Ferrer, Manuel; Bjerga, Gro Elin Kjæreng (Peer reviewed; Journal article, 2021)
      To support the bio-based industry in development of environment-friendly processes and products, an optimal toolbox of biocatalysts is key. Although functional screen of (meta)genomic libraries may potentially contribute ...